![]() ![]() The presence of AF at ICD/CRT-D implantation carries subsequent independent risks of 1.62-fold for death and 2.25-fold for inappropriate therapy.Ītrial fibrillation Implantable cardioverter Inappropriate therapy Mortality Nippon Storm study.Ĭopyright © 2021. Inappropriate ICD/CRT-D therapy occurred in 40/257 patients (15.6%) and AF was associated with a higher prevalence of inappropriate ICD/CRT-D therapy (p<0.0001 HR=2.25). ![]() Therefore, he was started on Tapazole on a dose of 5 mg p.o. His pacemaker/ICD was interrogated, and it confirmed appropriate shocks for ventricular tachycardia or ventricular flutter. In multivariate analysis, AF was significantly associated with all-cause mortality. He was again admitted to the hospital, due to multiple shocks from his defibrillator for ventricular tachyarrhythmia. During follow up, mortality was significantly higher in the AF than the non-AF group (p<0.0001). We identified all patients from January 2005 to February 2021 with atrial fibrillation who were started on AAD therapy with a Vaughn-Williams class IC agent (flecainide or propafenone) or class III agent (either sotalol or dofetilide, excluding amiodarone and dronedarone) at our institution. 61.4 years p<0.0001), and had lower left ventricular ejection fraction (38.0 ± 17.0% vs. Occurrence of VT/VF was associated with NT-proBNP, history of atrial fibrillation/flutter, male sex, lower ejection fraction, and history of hypertension. When the AF (n = 257, 16.6%) and non-AF-(n = 1292, 83.4%) groups were compared, the AF group was older (67.7 vs. We allocated 1549 participants to AF and non-AF groups, compared their clinical data at the time of enrollment, and monitored the incidences of mortality, hospitalization, and appropriate and inappropriate ICD/CRT-D therapy during a median 28 months. Supraventricular arrhythmias are a diverse group of atrial arrhythmias. We analyzed data from the Nippon Storm Study, a prospective observational study of 1570 patients that was conducted at 48 Japanese ICD centers. Atrial fibrillation and atrial flutter are the most common of these atrial arrhythmias, and the other less common supraventricular arrhythmias are atrial tachycardias, atrioventricular reentrant tachycardia, atrioventricular nodal tachycardia, and others. Although atrial fibrillation/flutter (AF) is the most common cardiac arrhythmia in patients with heart disease, the impact of AF on the prognosis of patients with ICD/CRT-D remains controversial. Implantable cardioverter-defibrillator and cardiac resynchronization therapy using a defibrillator (ICD/CRT-D) are established means of reducing mortality due to ventricular arrhythmia. ![]()
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